On Friday and Saturday Westfield Stratford City will be closed to members of the public without a ticket for the Olympic Games.
The shopping centre, which is adjacent to the Olympic Park, will only be accessible to accredited workers, members of the public with, or collecting, a Games ticket or using hospitality venues between 10:30am and 5pm on both days.
Over 200,000 spectators and accredited workforce are expected each day.
Transport for London said that tickets for the Games cannot be bought in Stratford and passengers should avoid the area.
LOCOG chief executive Paul Deighton said: “As we move into the second week of the Games the Olympic Park will be much busier as the Olympic Stadium hosts its first sporting events. This Friday and Saturday will be the busiest days of the Games, with more than 200,000 people travelling to the Olympic Park alone.
“Because of the huge number of people coming to the Park on those days at certain times we have to restrict general public access to Westfield Stratford City and we are encouraging people to avoid travelling to Stratford unless they have a ticket.”