The robbers - thought to be a gang of four men travelling on motorbikes - ram raided the store at midnight on Monday and took some of the most expensive bags in the collection including a bespoke crocodile Ebury worth up to £6,500. They also stole stock of Anya Hindmarch's key autumn bag, the Lautner, which sell for £555 each.
A spokeswoman for the company said: "Clearly it was people who knew what they were doing."
Anya Hindmarch is the latest in a long line of designers to be targeted by robbers and ram raiders. Last month both the Luella and FrostFrench London stores were ram raided and London Fashion Week designer Christopher Kane had his spring 08 samples stolen from his design studio a week before his catwalk show.
The Anya Hindmarch store remains open but has been boarded up for security. Stock has already been replenished.
Company founder Anya Hindmarch said: “It is extremely upsetting for our store to be attacked in this way and a huge amount of wasted energy to sort out. However given the frequency of these attacks it seems like you are no one unless you are ram raided these days!”
The police are investigating this latest incident and anyone with any information is urged to contact their local police.