Karen Millen has put at least 100 head office roles into consultation.
The news follows Karen Millen buying former sister brand Coast through a pre-pack administration two weeks ago.
A spokeswoman for Karen Millen said: “As is the case following any acquisition, it has been necessary for Karen Millen to undertake a careful review in order to rationalise and, in some cases, restructure roles and responsibilities, to ensure the business is positioned well for future growth. A full consultation process is under way and our priority is to work closely with and support staff throughout this.”
Coast appointed Mike Denny, Ian Green and Zelf Hussain of PwC as joint administrators of Coast Holdings Limited, Coast Retail Limited and Coast Fashions Limited on 11 October.
Karen Millen then bought the retailer’s UK concession portfolio, online business and franchise stores, saving 600 jobs.
Coast was previously owned by Aurora Fashions, which also owns Oasis and Warehouse.
Aurora is owned by Icelandic bank Kaupthing, which also owns Karen Millen.
Karen Millen sales slipped 1.2% to £158.8m in its most recent results for the year to 28 February 2017. In what was called a “year of change” by CEO Beth Butterwick, operating losses were cut by 12% to £9.2m compared with 2015/16.
Gross profit edged up 1.6% to £95.4m.