Marks & Spencer is proposing to axe 351 roles, following a review of its store management structure.
A total of 115 store, commercial and operations managers will be made redundant, along with 182 section managers and 54 visual managers.
A spokeswoman for M&S said: “M&S is transforming and this is a tough but necessary decision to take to ensure our stores support the future of the business and provide the best service for our customers.”
Last week M&S chairman Archie Norman suggested that more store closures may follow the 100 announced by the retailer in May.
Speaking at the business’s annual general meeting on 10 July Norman said: “I can’t tell you it won’t be the last.”
M&S chief executive Steve Rowe added: “There are likely to be more redundancies”.
Norman called the transformation programme the “biggest turnaround in UK retail”, explaining that M&S has “old stores in locations where people aren’t shopping any more”.
Pre-tax profits before one-off items at M&S fell by 5.4% to £580.9m for the year to 31 March compared with 2016/17, while revenue edged up 0.7% to £10.7bn.
Revenues for clothing and home at M&S fell 1.9% compared with 2017.