M&S has 200 positions up for grabs including 165 graduate roles in stores and head office, as well as 35 places on the company's Business Placement scheme.
Positions available include retail roles, HR roles, food technology, food buying and food product development as well as general buying positions, merchandising jobs and technology and design roles.
Successful graduate applicants will join the company in either April 2009 or September 2009.
To apply go to www.marksandspencer.com/gradcareers
Applications close on December 11.