UK customers can now buy and send clothes, lingerie and selected beauty and homewares to friends and family in France, Germany, Spain, the US, Canada, Australia and New Zealand in time for Christmas.
The move is part of Marks & Spencer's strategy to grow sales of M&S Direct to £500 million by 2011.
Director of international, home and direct Carl Leaver said: "Our decision to deliver internationally provides a significant opportunity for Marks & Spencer not only to grow sales of our ecommerce business, but to further extend our brand globally."
He added: "We have deliberately selected markets where we currently don't have stores."
Last orders to Australia and New Zealand are on December 4, to the US and Canada on December 9 and to Europe on December 11.
Deliveries will cost £10 to Europe and £20 to the other countries.