River Island and Matalan have signed up to the Bangladesh Fire and Building Safety Accord.
The two retailers join more than 80 worldwide that have signed up to the legally-binding agreement, pledging to contribute up to £325,000 a year towards independent factory inspections and fire safety measures.
River Island said it had signed the agreement following “careful consideration”.
In a statement, the business said: “Our objective throughout has been to establish a long-term framework for improving working conditions in the countries that we produce in.
“We feel the Accord is the best vehicle to bring about significant changes to the region. The final details of the Accord are still being established and we look forward to working closely with the Accord members to put the plan into action.”
Matalan said it was “committed to working with the steering group to help achieve its goals.”